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Home Blogs Professor Shane Darke's blog Xanax overdose and related deaths - a podcast Xanax overdose and related deaths - a podcast. Professor Shane Darke discusses the increase in deaths involving alprazolam also known by its brand name, Xanax. Listen to this podcast. Marion Downey, NDARC Communications Manager: Professor Shane Darke has recently completed a study which found a big increase in the number of sudden deaths and overdoses where the benzodiazepine alprazolam was involved.
Professor Darke, what are benzodiazepines? Professor Shane Darke: Benzodiazepines are tranquilisers and sleeping tablets. Shane Darke: We did the study because we were seeing evidence amongst drug users, and there was also anecdotal evidence, that there was a problem with this particular drug. And we thought well, what we need to look at is — I suppose you could call it — the pointy end of this: is it being involved in deaths?
Flumazenil is an injectable drug that reverses the effect of a benzodiazepine by blocking the benzodiazepine receptor. A doctor may give adults flumazenil injections if they have overdosed on benzodiazepines.
They can also give children aged 1—17 years flumazenil to reverse the effects of benzodiazepines after a surgical procedure. Usually, however, the risks of using flumazenil outweigh the possible benefits, so doctors do not recommend it routinely. A significant side effect of flumazenil is seizures, and the drug carries a black box warning to this effect.
This type of warning is the most serious warning that the FDA give to drugs. When doctors give people flumazenil, they must be prepared to treat and manage any seizures that occur. People who overdose on Xanax alone may have mild symptoms of toxicity. However, when people combine Xanax with other drugs that affect the CNS, they may experience more severe symptoms, including difficulty breathing, coma, and possibly death.
People taking Xanax must let their doctors and pharmacists know if they are also taking other medications. Some people try to harm themselves by taking large amounts of Xanax or combining Xanax with other drugs. Overdoses and misuse of Xanax can lead to coma and death. Dioxins are chemical compounds that are hazardous to health.
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Small pieces of plastic called microplastics can travel through wastewater into the ocean, where animals may eat them. Learn about plastics in seafood…. What to know about Xanax overdose. When consumed in large enough quantities, an overdose from Xanax can cause coma, respiratory depression, and death. We are here to help you through every aspect of recovery. Let us call you to learn more about our treatment options.
Xanax alprazolam is a medication most commonly prescribed for anxiety and panic disorders. As a high-potency benzodiazepine medication with a short half-life, Xanax is particularly attractive to recreational drug abusers. Research has found that Xanax is more toxic during overdose than other benzodiazepine drugs. Xanax has a great impact as a central nervous system CNS depressant.
CNS depressants cause critical life-support systems to slow. These include blood pressure, breathing, heart and temperature rates. The best way of preventing overdose is through abstinence. For active drug abusers, one of the most effective ways of preventing overdose is by recognizing the signs of intoxication. This knowledge can help to stop drug abuse before it progresses to this point.
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